Clinical Rationale & Evidence Base

The science behind
between-session practice.

This document sets out the evidence base for EMDR as an intervention, the rationale for between-session support tools, and the scope and limitations of Rewire as a practitioner-assigned adjunct. It is intended for qualified clinicians evaluating the platform for clinical use.

Clinical Advisory

Rewire is not a therapy platform. It does not provide psychological treatment, clinical assessment, diagnosis, or therapeutic intervention of any kind. It is a practitioner-assigned between-session support tool, designed to be used only under the supervision and clinical management of a qualified, licensed mental health professional trained in EMDR or a related trauma-informed modality. Rewire should not be used as a standalone intervention, as a substitute for therapy, or by individuals without an active therapeutic relationship with a qualified clinician. All clinical decisions — including whether a client is appropriate for between-session bilateral stimulation exercises — remain the sole responsibility of the supervising practitioner.

EMDR: the research
foundation.

Eye Movement Desensitization and Reprocessing (EMDR) was developed by Francine Shapiro, Ph.D., following her initial observations in 1987 and formalised in a landmark randomised controlled trial published in 1989. In the decades since, EMDR has accumulated one of the most robust evidence bases of any trauma-focused psychological intervention.

Foundational Research

Shapiro's original 1989 study demonstrated significant reductions in subjective distress in trauma survivors following eye movement desensitisation. Her subsequent development of the Adaptive Information Processing (AIP) model proposed a theoretical mechanism: traumatic memories become "frozen" in the nervous system in a form that cannot be fully integrated, and bilateral stimulation supports the brain's natural information-processing capacity to assimilate those memories adaptively.

"Subjects receiving EMD showed a significant decrease in disturbance related to traumatic memories and a significant positive change in beliefs about those memories."

Shapiro, F. (1989). Eye movement desensitization: A new treatment for post-traumatic stress disorder. Journal of Behavior Therapy and Experimental Psychiatry, 20(3), 211–217.

Shapiro's full formalisation of the eight-phase protocol, including the Adaptive Information Processing model, established the clinical framework that remains standard practice today.

Shapiro, F. (2001). Eye Movement Desensitization and Reprocessing: Basic Principles, Protocols, and Procedures (2nd ed.). Guilford Press.

International Clinical Endorsement

EMDR is now endorsed as an evidence-based treatment for PTSD and trauma-related conditions by the following bodies:

Meta-Analytic Evidence

Multiple high-quality meta-analyses have confirmed the efficacy of EMDR across populations and trauma types:

The Bilateral Stimulation Mechanism

The active ingredient most associated with EMDR's unique effect — bilateral stimulation (BLS) via eye movements, taps, or bilateral audio — is the subject of ongoing research. Leading hypotheses include:

While the precise mechanism remains under investigation, the therapeutic effect of BLS-supported trauma processing is well-established across multiple independent research groups and populations.

The rationale for
between-session support.

A consistent finding across psychotherapy research is that between-session engagement — practice, self-monitoring, and skill generalisation — predicts better treatment outcomes. In trauma-focused therapies, between-session work serves the additional function of consolidating and extending the regulatory gains made within sessions.

Between-Session Engagement in Trauma Treatment

Research consistently demonstrates that between-session practice and homework completion is positively associated with PTSD symptom reduction and treatment outcomes across modalities (Kazantzis et al., 2016). In EMDR specifically, therapists routinely assign grounding exercises, container techniques, safe/calm place visualisations, and resourcing practices for clients to use between sessions. These exercises serve to:

How Rewire Supports This Practice

Rewire provides a structured, clinician-assigned digital environment for clients to engage with between-session exercises. The platform is designed to:

All exercises available within Rewire are containment-focused and have been designed to be appropriate for independent use by clients within an active therapeutic relationship. They do not constitute trauma reprocessing and are not a substitute for EMDR therapy.

What Rewire is —
and what it is not.

Within scope

Between-session grounding

Structured, containment-focused exercises assigned by a clinician for independent use between appointments.

Outside scope

Trauma reprocessing

Active processing of target memories. Rewire does not facilitate or guide trauma reprocessing work. This must only occur within a supervised therapeutic session.

Within scope

Resourcing & stabilisation

Safe place, calm place, container exercises, and positive resource installation for nervous system regulation.

Outside scope

Clinical assessment

Rewire does not provide or assist with clinical assessment, diagnosis, risk formulation, or treatment planning.

Within scope

Session progress tracking

Pre/post nervous system state ratings and completion data for review by the assigning clinician.

Outside scope

Crisis intervention

Rewire is not designed for, and must not be used in, acute crisis situations. Users in crisis should contact their therapist or emergency services immediately.

Practitioner Considerations: Appropriate Use

Practitioners assigning Rewire to clients should consider the following contraindications and precautions, consistent with standard EMDR best-practice guidelines for between-session work:

  • Clients in the active destabilisation phase of treatment who do not yet have sufficient affect regulation capacity for independent practice
  • Clients with active psychosis, active substance use disorder, or severe dissociative disorders (DID, complex OSDD) where unsupervised BLS exercises may be contraindicated
  • Clients currently in acute crisis, experiencing suicidal ideation, or presenting with significant self-harm risk
  • Clients for whom the clinician has not yet completed a thorough trauma history and stabilisation assessment
  • Children and adolescents, unless the clinician has made a specific, documented clinical decision that use is appropriate and has obtained appropriate consent from a parent or guardian

Practitioner
responsibility.

Rewire is a tool for use by qualified practitioners. By assigning Rewire to clients, clinicians accept that:

Rewire is not responsible for, and cannot substitute for, the clinical judgment of the treating practitioner. If in doubt about whether between-session exercises are appropriate for a given client, err on the side of clinical caution.

Full reference
list.